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However, despite showing promising results, there was an increased incidence of side effects. Initial dose: 200 mg orally once a day at bedtime (usual dose in clinical trials); in rare cases, initial doses of 100 mg orally once a day at bedtime may be warranted in patients who have an increased response to verapamil (e. Your doctor may adjust your dose if needed Liquid verapamil contains 40mg in each 5ml spoonful. For oral dosing, verapamil (immediate-release) should be given 80 mg to 160 mg three times a day (TID). Maintenance dose: 5 to 10 mg orally once a day. Verapamil injection is given as an infusion into a vein, usually in an emergency situation. 17,9 The remaining parent drug undergoes O-demethylation, N-dealkylation, and N-demethylation to a number of different. 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